Chronic, low-grade inflammation in the body—a phenomenon known as “inflammaging” because it increases with age—has been linked to many of today’s leading causes of illness and death, including cancer, heart disease, metabolic conditions and neurodegenerative diseases. But scientists have struggled to understand what causes inflammaging or how to reverse its effects.

Researchers from the Keck School of Medicine of USC have identified the thymus, a small organ behind the breastbone that plays a central role in immune system development, as a key player in inflammaging. They discovered that thymulin, a hormone produced by the organ, keeps inflammation under control.

As we age, thymulin decreases and inflammation increases, allowing diseases like cancer to progress...

Stars and galaxies make up much of the universe’s ordinary, observable matter. But for decades, scientists have wrestled with a cosmic conflict: There should be much more.

Physicists have good estimates of how much matter was present in the early universe. Shortly after the Big Bang, roughly 83% of all matter in the universe was composed of invisible dark matter, with ordinary matter making up the rest...

Multiple sclerosis (MS) is a chronic autoimmune disorder that attacks the central nervous system. For years, Epstein-Barr virus (EBV) has been strongly linked to MS, as nearly every person diagnosed with the condition shows evidence of past EBV infection. For example, a 2022 study analyzed millions of U.S. military recruits and found that getting infected with EBV increased a person’s risk of developing MS 32-fold.

But exactly how EBV is linked to the abnormal immune response seen in MS has remained unclear until now.

In a study published in Science Translational Medicine, scientists descr...

Large language models (LLMs), the computational algorithms underpinning ChatGPT, Gemini and other artificial intelligence (AI)-powered conversational platforms, are now widely used worldwide. These models can rapidly answer questions, source information online, assist users with specific tasks and produce text tailored for specific purposes.

Over the past few years, computer scientists have introduced a wide range of LLMs, some of which can also complete tasks autonomously and take actions on a user’s behalf, for instance, answering messages, scheduling online appointments or updating programming code...