Immune changes could signal inflammatory bowel disease up to 10 years before diagnosis

ulcerative colitis
Endoscopic image of a bowel section known as the sigmoid colon afflicted with ulcerative colitis. The internal surface of the colon is blotchy and broken in places. Credit: Samir/Wikipedia

A large-scale study, presented at UEG Week 2026, has identified distinct antibody patterns up to 10 years before the diagnosis of inflammatory bowel disease (IBD), potentially opening new avenues for earlier risk detection and providing insights into future disease course.

IBD is a group of chronic conditions, including Crohn’s disease (CD) and ulcerative colitis (UC), in which abnormal immune responses contribute to ongoing inflammation and damage in the digestive system...

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Mini brain organoids ‘read’ braille in key step toward biohybrid computing

Mini brain organoids 'reading' Braille marks key step towards biohybrid computing
The tactile sensor that scanned braille letters. Credit: Dr. Benjamin Ward-Cherrier

Could computers include tiny brain organoids one day? The human brain is an incredibly energy-efficient computer, and silicon processors that try to imitate it achieve huge energy savings over traditional processors. Now scientists are experimenting with using organoids modeled on the human forebrain to develop energy-efficient biohybrid computing.

A crucial first step toward this is learning whether the organoids can receive and relay signals reliably, which a Bristol-based team of researchers investigated using braille letters. They found that teams of three brain organoids produced signals that accurately corresponded to different letters 83% of the time.

“We can take information from a real ta...

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Salt crystals could hold clues to life beneath Enceladus’s ice

Enceladus
Saturn’s moon Enceladus. Credit: NASAh

The ocean beneath Saturn’s moon Enceladus lies under kilometers of ice, but some of its contents do reach the surface. Jets near the south pole spray out water vapor and icy particles, offering a way to investigate the hidden ocean without drilling down to it.

The challenge is knowing which material preserves the most useful clues. A new laboratory study points to a possible target: salt crystals that trap tiny pockets of water as they grow during freezing.

Liam Perera of Diamond Light Source in the United Kingdom and colleagues found these pockets inside natron, a sodium carbonate mineral expected to form on Enceladus...

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Quantum magic state cleanup cuts errors 40-fold in first successful hardware test

New error-correction technique could dramatically improve the reliability of quantum computers
Details of magic state cultivation. Credit: Science (2026). DOI: 10.1126/science.aee7961

Qubits, the quantum equivalent of digital bits, are fragile and prone to errors. That makes building reliable quantum computers extremely difficult. One fix has been to use traditional magic state distillation, which filters out flaws, but it is extremely resource-intensive.

Another potential solution is magic state cultivation, which cleans up a noisy magic state (a specially prepared quantum state that is needed for advanced calculations) directly inside a protected qubit. But this approach has never been tested successfully on real hardware.

However, in a first for quantum computing, Google Quantum AI researchers have demonstrated magic state cultivation on Willow, a superconducting proces...

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