AI‑designed gene‑editing enzymes expand the CRISPR toolbox

AI model designs RNA-guided nucleases that surpass natural nuclease abilities, expanding CRISPR toolbox
RNA-guided nuclease TnpB design strategy with an ESM Inverse Folding (ESM-IF1) model. Credit: Science (2026). DOI: 10.1126/science.aed6123

Scientists have made many advances using traditional CRISPR technology, especially in medicine, but they are now seeking ways to create genuinely new gene-editing enzymes with properties that have not already evolved naturally. A new study, published in Science, describes a new AI-designed synthetic TnpB enzyme, called SynTnpBs, that has outperformed the natural reference enzyme.

Creating new gene editors
CRISPR tools use a programmable guide RNA to direct an enzyme to a specific target in the genome to edit (cut, insert or correct) DNA. The TnpB enzyme is a compact ancestor of certain CRISPR enzymes, called CRISPR-Cas12 enzymes...

Read More

NASA’s Psyche mission delivers Mars flyby data, time-lapse video

An overhead satellite mosaic of the Martian surface, showing numerous impact craters in a transition zone of reddish-brown and dusty blue terrain, with streaks stretching across the blue region.
Captured by the multispectral imager instrument on NASA’s Psyche mission, this is an enhanced-color mosaic created from four individual images acquired on May 15, 2026, during the spacecraft’s flyby of Mars. 
Credit: NASA/JPL-Caltech/ASU

The spacecraft aced its encounter with Mars. Now, mission scientists are studying a trove of data from the flyby in preparation for its arrival at asteroid Psyche in 2029.

NASA’s Psyche spacecraft flew by Mars on May 15, using the planet’s gravity to gain speed and slightly tilt its trajectory. The flyby also gave the team an opportunity to prepare for the science they will conduct when they reach the metal-rich asteroid Psyche in 2029.

Using Mars as a stand-in for the asteroid during the flyby, the team could test the spacecraft’s science i...

Read More

Quantum teleportation could reduce photon loss in long-distance communications

Artistic illustration of lossless quantum teleportation. Credit: Li-Chao Peng.

Quantum technologies, which leverage the principles of quantum mechanics, have been found to outperform their classical counterparts on specific tasks. Among other things, past studies have highlighted the potential of quantum systems that can enable long-distance communication, using photons (i.e., particles of light) to carry quantum information.

Despite their promise, quantum communication systems are often prone to photon loss, the scattering, absorption or disappearance of traveling photons. This photon loss becomes increasingly pronounced as transmission distances increase.

One proposed approach for reducing photon loss relies on a process known as quantum teleportation...

Read More

Nearby rocky may be replenishing helium from atmosphere, study finds

Nearly a decade after the discovery of LHS 1140b, a rocky exoplanet in the habitable zone of a nearby low-mass star, a new study reveals that the object may have its own atmosphere.

University of Florida Assistant Professor of Astronomy Jason Dittmann first discovered the planet in 2016. Now, he is a co-author of the new study, published in Science, that uses helium escape to explain a potential atmosphere.

“The exciting part about this paper, and why I think it was accepted into Science, was that this is the first time that we’re seeing a rocky, Earth-like planet that could still have an atmosphere,” Dittmann said.

How the planet was found
The Magellan Clay telescope at Las Campanas Observatory in Chile showed evidence of helium escaping from the planet...

Read More