Circadian rhythm drives metabolic dysfunction in fat cells, study finds

Joseph Bass, MD, PhD, the Charles F. Kettering Professor of Endocrinology and Metabolism and director of the Center for Diabetes and Metabolism, was senior author of the study published in Nature Metabolism. 

Northwestern Medicine scientists led by Joseph Bass, MD, Ph.D., the Charles F. Kettering Professor of Endocrinology and Metabolism and director of the Center for Diabetes and Metabolism, have discovered how disruptions in the circadian rhythm impair metabolic function in fat cells, providing new insights into the molecular mechanisms that cause obesity and metabolic disease, according to a recent study published in Nature Metabolism.

“It’s not simply the accrual of excess fat that leads to disease...

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Nearby red dwarf star hosts at least four planets—with one in the habitable zone

Nearby red dwarf star hosts at least four planets—with one in the habitable zone
sBGLS periodograms of all planet candidates and the rotation period of the star. The apparent fringe pattern in all panels is caused by the sampling of the data in two chunks separated by approximately 13 y. Credit: Astronomy & Astrophysics (2026). DOI: 10.1051/0004-6361/202554984

In 2020, a study confirmed that two planets orbited the nearby red dwarf, GJ 887. Now, astronomers have confirmed the existence of two additional planets orbiting GJ 887 in a new study published in Astronomy and Astrophysics. The new study suggests that one of these newly confirmed planets is in the habitable zone.

The GJ 887 red dwarf system
GJ 887 is a bright red dwarf star about 10.7 light years away from our solar system—a relatively short distance compared to other star systems...

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Tubulin prevents toxic protein clumps in the brain, fighting back against neurodegeneration

Tubulin prevents toxic protein clumps in the brain, fighting back neurodegeneration
WT Tau/αSyn Endogenous Colocalization in Cells and Tau/αSyn/Tubulin Confocal Phase Diagram. Credit: Nature Communications (2026). DOI: 10.1038/s41467-026-69618-3

Researchers at Baylor College of Medicine have discovered a potential new strategy to fight back against Alzheimer’s and Parkinson’s diseases, conditions that are linked to the toxic accumulation of Tau and alpha synuclein protein clumps in the brain. The team reports in Nature Communications that tubulin, the building block of microtubules, the cell’s internal ‘railway tracks,” can stop Tau and alpha synuclein from forming toxic clumps and instead steer them into their normal, healthy roles.

“Tau and alpha synuclein are well known for their roles in neurodegenerative diseases like Alzheimer’s and Parkinson’s...

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Robots that refuse to fail: AI evolves ‘legged metamachines’ that reassemble and withstand injury

Evolved robots are born to run and refuse to die
Called “legged metamachines,” the creations are made from autonomous, Lego-like modules that snap together into an endless number of configurations. Credit: Sam Kriegman/Northwestern University

Northwestern University engineers have developed the first modular robots with athletic intelligence. They can be combined and recombined in the wild, recover from injury and keep moving no matter what’s thrown at them.

Called “legged metamachines,” the creations are made from autonomous, Lego-like modules that snap together into an endless number of configurations. Each module by itself is a complete robot with its own motor, battery and computer. Alone, a module can roll, turn and jump. But the real agility and indestructibility emerges when the modules combine.

The study was published i...

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