Umbilical cord blood transplant with pooled stem cell product shows 96% survival and no GVHD in leukemia patients

A new way of using umbilical cord blood for treating blood diseases could make the treatment more accessible to patients who need a stem cell transplant. A Phase II clinical trial of patients undergoing a cord blood transplant plus a stem cell product derived from pooled cord blood units showed that 27 of 28 patients (96%) with leukemias and GVHD survived at least one year and none of the patients experienced severe acute or chronic graft-versus-host disease, which are common complications of stem cell transplantation.

The results have been published in the Journal of Clinical Oncology.

“This is the first time transplant patients received cells from what amounts to nine different human beings,” said the study’s principal investigator, Filippo Milano, MD, Ph.D...

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Low-cost 3D printers could gain medical-grade precision from ultrathin light-control film

Ultra-thin optical film sharpens 3D printing precision
Researchers designed and fabricated a double-sided structure collimation film (DSSCF) with better collimation characteristics thanks to additional trapezoidal microstructures that prevent the large-angle leakage light seen with single-sided structure collimation film (SSSCF). The DSSCF also improves the light intensity uniformity when combined with a diffuser module. Credit: Ding-Zheng Lin, National Taiwan University of Science and Technology

Researchers have developed an ultra-thin optical film that improves the quality of the light used in LCD resin-based 3D printers. The advance helps ensure that tiny details are reproduced with precision, which could make it possible to 3D-print medical-grade or industrial-grade products at a lower cost.

Resin-based 3D printing, or vat photopoly...

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Why stars spin down, or up, before they die

Why stars spin down, or up, before they die
Illustration of the inner regions of a massive star during its final oxygen (green) and silicon (teal) shell burning phase, before the collapse of the iron core (indigo). The strength and geometry of the magnetic field, combined with the properties of convection in the oxygen region can cause the rotation rate to speed up or slow down. Credit KyotoU / Lucy McNeill

From birth to death, stars generally slow by 100 to 1,000 times their initial rotation rates; in other words, they “spin down.” The sun’s total angular momentum has declined as material is gradually blown off at the surface as solar wind. By observing this, astronomers have theorized the interaction between magneticfields and plasma flow to be the most efficient way to spin down stars.

Why and how this happens has long int...

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Water-based zinc batteries tackle a barrier that has long blocked cheap, stable renewable energy storage

New aqueous electrolytes boost the efficiency and stability of zinc metal batteries
Dejian Dong, the first author of the article, examines a freshly prepared electrolyte sample in the laboratory. Credit: Dong et al.

Renewable energy technologies, such as solar cells and wind turbines, are becoming increasingly widespread in many countries worldwide. Reliably storing the electricity produced by these devices, so that it can be used later at times when sunlight or wind are scarce, would further improve their effectiveness as sustainable energy solutions.

A promising solution to store solar and wind energy entails the use of aqueous zinc (Zn) metal batteries. These are low-cost, safe and environmentally friendly batteries that store and release energy, leveraging water-based solutions and Zn anodes.

Despite their potential, Zn batteries have not yet achieved the de...

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