Immune proteins offer new clues to how prostate cancer could be prevented

Prostatic adenocarcinoma, Gleason Pattern 4

A new study led by researchers at Oxford Population Health shows that higher levels of proteins involved in activating and coordinating the immune system were associated with a lower risk of developing prostate cancer. The findings suggest that the body’s ability to recognize and respond to abnormal cells may play an important role in the early development of prostate cancer and could point to new approaches for preventing the disease.

The study, published in Nature Communications, is the largest and most comprehensive prospective and genetic analysis of circulating immune and inflammation-related proteins in relation to prostate cancer risk. Prostate cancer is the most common cancer in U.K...

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A quantum breakthrough makes light behave like both a solid and a liquid

Bizarre Quantum Matter at Room Temperature
A supersolid is an extraordinary state of matter that combines superfluidity with the spontaneous formation of a periodic, crystal-like structure. Credit: Marcin Muszyński, Faculty of Physics, University of Warsaw

Scientists have observed a bizarre quantum state of matter that combines the structure of a crystal with the frictionless flow of a liquid, all at room temperature. The breakthrough overturns a major practical limitation of exotic quantum experiments and could help bring powerful new light-based computing and sensing technologies closer to reality.

Scientists have demonstrated an extraordinary form of quantum matter that combines two properties that seem incompatible...

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Comets may have destroyed life’s ingredients instead of delivering them to Earth

Comets May Not Have Seeded Life on Earth
Illustration of cometary impact. Credit: Scarlett White

A century-old theory about the origins of life on Earth may be wrong. New research from the University of Cambridge suggests that comets traveled too fast and struck at unfavorable angles for the fragile molecules needed for life to survive, making successful delivery extraordinarily unlikely. Surprisingly, Mars may have had a better chance of receiving these cosmic ingredients, although even there the odds were slim. The findings point toward asteroids or chemical processes on Earth as more plausible sources of life’s building blocks.

For nearly a century, scientists have considered the possibility that comets helped make life on Earth possible by delivering essential organic molecules from space...

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Experimental weight-loss drug eases painful knee osteoarthritis in two clinical trials

painful knee
Credit: Unsplash/CC0 Public Domain

For people with painful knee osteoarthritis (OA) who are overweight or have obesity, everyday activities such as walking, climbing stairs and standing up from a chair can be difficult. In two Northwestern University–led Phase III clinical trials involving more than 1,000 participants combined, those taking the highest dose of retatrutide, a new experimental weight-loss injectable drug, lost about one-quarter of their body weight on average.

A pooled analysis of the studies found that about two-thirds of participants receiving retatrutide experienced at least a 50% reduction in knee pain, compared with 38% of those receiving placebo.

In addition to weight loss and pain relief, participants experienced other significant benefits, including reduc...

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