Category Biology/Biotechnology

Physical pain is essential for survival, as it allows animals to detect when they are injured or unwell, seek shelter and address their ailments. Yet when it becomes chronic, pain can also become highly distressing and debilitating.

While there are now several therapeutic strategies for managing chronic pain, an emerging one that has been found to be particularly promising is vagus nerve stimulation (VNS). VNS entails the delivery of mild electrical pulses to the nerve that connects the brain to organs throughout the body.

Past studies suggest that VNS-based therapy can reduce the pain associated with various medical conditions, including chronic headaches, fibromyalgia and joint inflammation. The neural processes by which it can ease pain, however, are still poorly understood.

Saturn’s largest moon, Titan, is a unique environment in our solar system. It is the only moon (or body beyond Earth) to have a dense, nitrogen-rich atmosphere, and its methane cycle is very similar to Earth’s hydrological cycle, in which solid and liquid methane evaporate to form clouds and return to the surface as precipitation. In addition, its prebiotic surface environment and rich organic chemistry make it a prime destination for astrobiology missions, such as NASA’s Dragonfly mission (set to launch no earlier than July 2028).

And as Robert Zubrin said in his book, “Entering Space: Creating a Spacefaring Civilization,” Saturn’s moons could become the “Persian Gu...

Though protein clumps associated with Alzheimer’s and Parkinson’s were discovered more than a century ago, researchers remain largely unable to prevent them from forming or eliminate them from the brain. And though a variety of therapies have taken aim at tau tangles, beta-amyloid plaques and Lewy bodies, among other notorious aggregates, none have been very effective at stopping disease progression.

Rockefeller’s Hermann Steller and his team in the Strang Laboratory of Apoptosis and Cancer Biology have long been fo...

The first human clinical trial of a universal Sarbeco coronavirus vaccine, developed by the University of Cambridge and spin-out DIOSynVax (DVX) Ltd, has shown that the vaccine is safe and has no significant side effects.

The trial, involving 39 healthy volunteers, tested a vaccine designed to provide protection against multiple Sarbeco coronaviruses—the large group of viruses that occur in nature including SARS-CoV-2, which caused the COVID pandemic.

The vaccine triggered immune responses in the volunteers not only to SARS-CoV-2 and SARS, but to related bat viruses that could potentially jump from animals to humans and cause future pandemics.

This trial proves the safety of an entirely new way of designing vaccines...