Category Biology/Biotechnology

A set of neurons identified by Scripps Research scientists influence the start of eating and drinking. Do you grab a fork and take a first bite of cake, or say no and walk away? Our motivation to eat is driven by a complex web of cells in the brain that use signals from within the body, as well as sensory information about the food in front of us, to determine our behaviors. Now, Scripps Research scientists have identified a group of neurons in a small and understudied region of the brain — the parasubthalamic nucleus (PSTN) — that controls when an animal decides to take a first bite of food.

In the study, published in Molecular Psychiatry on July 4, 2024, the team of scientists set out to selectively manipulate a group of PSTN cells that dial up their activity during periods of bi...

In an analysis of more than 50,000 individuals from around the world, carriers of gut Blastocystis, a single-celled organism that has been labeled either a parasite or harmless organism but is commonly found in the digestive system, was linked to indicators of good cardiovascular health and decreased body fat.

The research is published in Cell by an international team led by investigators at Massachusetts General Hospital (MGH).

“Blastocystis’ effects on health and disease are controversial and likely context-dependent, but our research suggests that it may play a beneficial role in how diet impacts human health and disease,” said co-lead author Long H...

Researchers led by Yasuhiro Murakawa at the RIKEN Center for Integrative Medical Sciences (IMS) and Kyoto University in Japan and IFOM ETS in Italy have discovered several rare types of helper T cells that are associated with immune disorders such as multiple sclerosis, rheumatoid arthritis, and even asthma...

Researchers at the University of Bonn have isolated a DNA molecule that is suitable for combating allergic contact dermatitis in mice. The aptamer binds to certain immune system messenger substances, rendering them ineffective. This even works if the active ingredient is applied to the skin in the form of an ointment.

The working groups involved hope that aptamer creams such as this could also be suitable for treating other skin conditions...