Category Biology/Biotechnology

Berberine could treat Eczema-Exacerbated Staph Infections, finds study

Staphylococcus aureus
Credit: CC0 Public Domain

Eczema, a skin inflammatory disease that causes dry, itchy and inflamed skin, affects millions worldwide. Eczema is associated with an altered skin microbiome and higher colonization by Staphylococcus aureus.

A study, led at New York Medical by postdoctoral fellow Anish R. Maskey, Ph.D., focuses on the natural compound berberine and its impact on eczema exacerbated by S. aureus. The findings, presented at ASM Microbe, shed light on berberine’s ability to inhibit S. aureus colonization and alleviate eczema symptoms without adverse effects.

Current treatments often fall short—topical antibiotics can give temporary relief, but risk development of antibiotic resistance, and steroid use can potentially result in topical steroid withdrawal (TSW) syndrome...

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Putting the Brakes on Chronic Inflammation

Gregory Sonnenberg IBD
An overactive immune response can result in autoimmune diseases including inflammatory bowel disease, psoriasis, rheumatoid arthritis and multiple sclerosis. Credit: Ella Marushchenko and Kate Zvorykina (Ella Maru Studio)

Scientists at Weill Cornell Medicine discovered a previously unknown link between two key pathways that regulate the immune system in mammals — a finding that impacts our understanding of chronic inflammatory bowel diseases (IBD). This family of disorders severely impacts the health and quality of life of more than 2 million people in the United States.

The immune system has many pathways to protect the body from infection, but sometimes an overactive immune response results in autoimmune diseases including IBD, psoriasis, rheumatoid arthritis and multiple scler...

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Safer Virus helps Eliminate Cancer in Mouse study

Safer virus helps eliminate cancer

Northwestern Medicine scientists have discovered that an attenuated (weakened) virus can help eliminate cancer in mice. In addition, mice that were treated with this virus were more resistant to developing tumors later in life.

The attenuated virus—lymphocytic choriomeningitis virus (LCMV)—works and is safe even in immunosuppressed mice. That’s a critical finding, as many cancer patients undergoing chemotherapy and other cancer treatments have suppressed immune systems.

“An important aspect about this viral-based therapy is that it demonstrates safety and efficacy even in an immunosuppressed host,” said corresponding author Pablo Penaloza-MacMaster, an assistant professor of microbiology-immunology at Northwestern University Feinberg School of Medicine...

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Algae offer Real Potential as a Renewable Electricity Source, research shows

Algae offer real potential as a renewable electricity source, new Concordia research shows
Credit: Uros Miloradovic on Unsplash

The need to transition away from fossil fuels to more sustainable energy production is critical. That’s why a team of Concordia researchers is looking at a potential power source that not only produces no carbon emissions but removes carbon as it works: algae.

Researchers at the Optical-Bio Microsystems Lab recently published a new paper on this topic in the journal Energies. In it, they describe their method of extracting energy from the photosynthesis process of algae suspended in a specialized solution and housed in small power cells. Configured correctly, these cells can generate enough energy to power low- and ultra-low power devices such as Internet of Things (IoT) sensors.

“The idea of the micro photosynthetic power cell is to extract e...

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