Category Biology/Biotechnology

Drug-like Inhibitor shows Promise in Preventing Flu

Compound 7, a molecular inhibitor of the influenza virus, interacting with the influenza virus’ hemagglutinin protein. Credit: Scripps Research

Currently available flu medications only target the virus after it has already established an infection, but what if a drug could prevent infection in the first place? Now, scientists at Scripps Research and the Albert Einstein College of Medicine have designed drug-like molecules to do just that, by thwarting the first stage of influenza infection.

The drug-like inhibitors block the virus from entering the body’s respiratory cells — specifically, they target hemagglutinin, a protein on the surface of type A influenza viruses...

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Creativity and Humor shown to Promote Well-Being in Older Adults via Similar Mechanisms

creative senior
Credit: cottonbro studio from Pexels

Many people associate aging with a decline in cognitive function, health issues, and reduced activity. Uncovering mental processes that can boost the well-being of the older adults could be highly beneficial, as it could help to devise more effective activities aimed at improving their quality of life.

Researchers at University of Brescia and the Catholic University of the Sacred Heart recently carried out a study investigating the contribution of creativity and humor to the well-being of the elderly. Their findings, published in Neuroscience Letters, show that these two distinct human experiences share common psychological and neurobiological processes that promote well-being in older adults.

“Our recent study belongs to a line of research ai...

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Celiac Disease: New Findings on the Effects of Gluten

Electron transmission micrograp
© Bielefeld University

An electron transmission micrograph from the study shows the problematic peptide 33-mer DGP with spiky structures that can open the intestinal barrier.

New details on how certain gluten-derived molecules trigger leaky gut syndrome in affected individuals. Celiac disease is a chronic autoimmune condition that occurs in around one per cent of the world’s population. It is triggered by the consumption of gluten proteins from wheat, barley, rye and some oats. A gluten-free diet protects celiac patients from severe intestinal damage. Together with colleagues, chemist Dr Veronica Dodero from Bielefeld University was able to determine new details on how certain gluten-derived molecules trigger leaky gut syndrome in celiac disease.

The key finding of the study: a part...

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The Crystallization of Memory: Study reveals how Practice forms New Memory Pathways in the Brain

Brain made from wooden puzzles.
Credit: Getty Images/iStockphoto

A new study led by UCLA Health has shown that repetitive practice not only is helpful in improving skills but also leads to profound changes in the brain’s memory pathways.

The research, published in the journal Nature and co-led by Rockefeller University, sought to unravel how the brain’s ability to retain and process information, known as working memory, improves through training.

To test this, researchers tasked mice with identifying and recalling a sequence of odors over the course of two weeks. Researchers then tracked neural activity in the animals as they practiced the task by using a novel, custom-built microscope to image cellular activity in up to 73,000 neurons simultaneously throughout the cortex.

The study revealed a transformation...

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