Category Biology/Biotechnology

How Obesity Dismantles our Mitochondria: Study reveals Key Mechanism behind Obesity-related Metabolic Dysfunction

mitochondria
These colored streaks are mitochondrial networks within fat cells. Researchers from UC San Diego discovered that a high-fat diet dismantles mitochondria, resulting in weight gain. Photo credit: UC San Diego Health Sciences

The number of people with obesity has nearly tripled since 1975, resulting in a worldwide epidemic. While lifestyle factors like diet and exercise play a role in the development and progression of obesity, scientists have come to understand that obesity is also associated with intrinsic metabolic abnormalities.

Now, researchers from University of California San Diego School of Medicine have shed new light on how obesity affects our mitochondria, the all-important energy-producing structures of our cells.

In a study published in Nature Metabolism, the researcher...

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Playing an Instrument linked to better Brain Health in Older Adults

accordian

Playing an instrument linked to better brain health in older adults

Engaging in music throughout your life is associated with better brain health in older age, according to a new study published by experts at the University of Exeter.

Scientists working on PROTECT, an online study open to people aged 40 and over, reviewed data from more than a thousand adults over the age of 40 to see the effect of playing a musical instrument—or singing in a choir—on brain health. Over 25,000 people have signed up for the PROTECT study, which has been running for 10 years.

The team reviewed participants’ musical experience and lifetime exposure to music, alongside results of cognitive testing, to determine whether musicality helps to keep the brain sharp in later life.

The paper, “The...

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3D-Printed Electronic Skin provides promise for Human-Machine Interaction

3D printed electronic skin provides promise for human-machine interaction
Credit: INMYWORK Studio

With more than 1,000 nerve endings, human skin is the brain’s largest sensory connection to the outside world, providing a wealth of feedback through touch, temperature and pressure. While these complex features make skin a vital organ, they also make it a challenge to replicate.

By utilizing nanoengineered hydrogels that exhibit tunable electronic and thermal biosensing capabilities, researchers at Texas A&M University have developed a 3D-printed electronic skin (E-skin) that can flex, stretch and sense like human skin.

“The ability to replicate the sense of touch and integrate it into various technologies opens up new possibilities for human-machine interaction and advanced sensory experiences,” said Dr...

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‘Cancer-Cooling’ Protein puts Bowel Cancer on Ice

digestive system
Credit: Pixabay/CC0 Public Domain

A protein in the immune system can be manipulated to help overcome bowel cancer, according to new research from The Australian National University (ANU). The research is published in Science Advances.

Bowel cancer claims more than 100 lives in Australia each week, yet around 90% of cases can be successfully treated if detected early.

According to lead author Dr. Abhimanu Pandey, from ANU, the protein, known as Ku70, can be activated or “turned on” like a light switch by using a combination of new and existing drugs.

“In its activated state, the protein acts like a surveillance system, detecting signs of damaged DNA in our cells,” Dr. Pandey said.

“DNA is the genetic code of life...

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