The top row depicts immature human heart muscle cells generated from stem cells. Their shape and fibre organisation is irregular. Upon Rbfox1 expression, the cells, as seen in the lower row, are more organised, closer to the shape and organisation of mature muscle cells in an adult heart. (Credit:[Huang J, Lee JZ, Rau CD, et al. Regulation of postnatal cardiomyocyte maturation by an RNA splicing regulator rbfox1. Circulation. 2023;148(16):1263-1266. doi: 10.1161/circulationaha.122.061602)
Researchers identify RBFox1 as a key intrinsic regulator of heart muscle cell maturation, overcoming a major limitation in cardiac regenerative therapy and disease modelling and demonstrating for the first time that RNA splicing control can significantly impact this process.
With more of us looking for alternatives to eating animals, new research has found a surprising environmentally friendly source of protein – algae.
The University of Exeter study has been published in The Journal of Nutrition and is the first of its kind to demonstrate that the ingestion of two of the most commercially available algal species are rich in protein which supports muscle remodeling in young healthy adults. Their findings suggest that algae may be an interesting and sustainable alternative to animal-derived protein with respect to maintaining and building muscle.
Researcher Ino Van Der Heijden from the University of Exeter said: “Our work has shown algae could become part of a secure and sustainable food future...
Researchers have created an Artificial Intelligence tool that uses sequences of life events—such as health history, education, job and income—to predict everything from a person’s personality to their mortality.
Built using transformer models, which power large language models (LLMs) like ChatGPT, the new tool, life2vec, is trained on a data set pulled from the entire population of Denmark—6 million people. The data set was made available only to the researchers by the Danish government.
The tool the researchers built based on this complex set of data is capable of predicting the future, including the lifespan of individuals, with an accuracy that exceeds state-of-the-art models...
Researchers at Karolinska Institutet and Danderyd Hospital have followed recipients of the new updated COVID-19 vaccine and analyzed the antibody response to different SARS-CoV-2 variants. The results show a surprisingly strong response to the now dominant and highly mutated omicron variants.
The ongoing COMMUNITY study, which was launched in the spring of 2020 with the regular testing of 2,149 members of the Danderyd Hospital staff, has recently published the results of this autumn’s leg of the study.
Twenty-four participants were recorded in this study, the majority of whom were over 64 and had received four or five previous vaccine doses...
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