Category Health/Medical

Researchers chart course for the design, testing, and implementation of next-gen AI in medicine.

Most medical AI models in use today are trained to perform one or two specific tasks and have limited utility. Next-generation AI — called generalist medical AI — incorporates various types of data to perform a variety of complex tasks in a range of clinical scenarios. Generalist medical AI can reshape medicine by augmenting clinical decision-making, real-time surgical and bedside support, and more.

The vast majority of AI models used in medicine today are “narrow specialists,” trained to perform one or two tasks, such as scanning mammograms for signs of breast cancer or detecting lung disease on chest X-rays.

But the everyday practice of medicine involves an endless array of clin...

Human lifespan is related to the aging of our individual cells. Three years ago a group of University of California San Diego researchers deciphered essential mechanisms behind the aging process. After identifying two distinct directions that cells follow during aging, the researchers genetically manipulated these processes to extend the lifespan of cells.

As described in a new article published April 27, 2023, in Science, the team has now extended this research using synthetic biology to engineer a solution that keeps cells from reaching their normal levels of deterioration associated with aging.

Cells, including those of yeast, plants, animals and humans, all contain gene regu...

An international team of medical researchers has found a link between major depressive disorder (MDD) and an interplay between the gut microbiome and the blood metabolome. For their study, reported in the journal JAMA Psychiatry, the group analyzed data in the UK Biobank.

Some prior research has suggested there may be a link between MDD and conditions surrounding the gut biome, but little work has been done to prove a connection, and existing studies were too small to show any true connections. In this new effort, the researchers attempted to conduct a far more broad study of any such connections by studying data in the UK Biobank—a massive database of health and genetic information for nearly a half-million patients in the U.K.

The researchers...

Typically T cells of the immune system respond to a specific feature (antigen) of a microbe, thereby generating protective immunity. As reported in the journal Immunity, an international team of scientists have discovered an exception to this rule...