Category Health/Medical

Researchers discover how Long-lasting Memories Form in the Brain

Researchers discover how long-lasting memories form in the brain
Graphical abstract. Credit: Neuron (2023). DOI: 10.1016/j.neuron.2023.04.005

Helping your mother make pancakes when you were three…riding your bike without training wheels…your first romantic kiss: How do we retain vivid memories of long-ago events? As described in a paper published in Neuron, researchers at Albert Einstein College of Medicine have found the explanation.

“The ability to learn new information and store it for long periods is one of the brain’s most remarkable features,” said Robert H. Singer, Ph.D., a co-corresponding author of the paper. “We’ve made a startling discovery in mice regarding the molecular basis for making those long-term memories.” Dr. Singer is professor of cell biology and in the Dominick P...

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Too Much Insulin can be as Dangerous as Too Little

person taking an insulin shot
Millions of Americans use insulin injections to boost levels and treat diabetes, but too much insulin can be deadly too. Researchers have identified a key player in preventing “insulin shock” that might also prove an effective alternative to the hormone. Agamatrix

Researchers describe a key player in the defense mechanism that safeguards against excessive insulin in the body, which can be as harmful as too little. Just over a century has passed since the discovery of insulin, a time period during which the therapeutic powers of the hormone have broadened and refined. Insulin is an essential treatment for type 1 diabetes and often for type 2 diabetes, as well. Roughly 8.4 million Americans use insulin, according to the American Diabetes Association.

One hundred years of research ...

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New Injectable Cell Therapy could Resolve Osteoarthritis

Wake Forest Institute for Regenerative Medicine (WFIRM) scientists have created a promising injectable cell therapy to treat osteoarthritis that both reduces inflammation and also regenerates articular cartilage. Recently identified by the Food and Drug Administration as a public health crisis, osteoarthritis affects more than 520 million people worldwide who deal with pain and inflammation. Osteoarthritis is typically induced by mechanical or traumatic stress in the joint, leading to damaged cartilage that cannot be repaired naturally.Read More

Common Infections linked to Poorer Cognitive Performance in Middle-Aged and Older Adults

elderly man doing puzzle

Findings, based on an analysis of 575 study participants, support the hypothesis that infections may negatively affect brain health. A new study from a team led by researchers at the Johns Hopkins Bloomberg School of Public Health found that signs of common infections in a sample of middle-aged and older adults were associated with poorer performance on a test of global cognitive function.

The results add to a growing body of evidence suggesting that infections in mid- and late-life can worsen cognitive performance and may increase the risk of Alzheimer’s disease and other dementias.

For their analysis, the researchers examined antibody levels to five common pathogens in 575 adults, ages 41 to 97...

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