Category Health/Medical

Mechanism found to Determine Which Memories Last

CREDIT: GETTY/ANDRIY ONUFRIYENKO

Neuroscientists have established in recent decades the idea that some of each day’s experiences are converted by the brain into permanent memories during sleep the same night. Now, a new study proposes a mechanism that determines which memories are tagged as Important enough to linger in the brain until sleep makes them permanent.

Led by researchers from NYU Grossman School of Medicine, the study revolves around brain cells called neurons that “fire” – or bring about swings in the balance of their positive and negative charges — to transmit electrical signals that encode memories...

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Researchers Turn Sack the Clock on Cancer Cells to offer New Treatment Paradigm

First author Sandi Radko-Juettner, PhD, a former St. Jude Graduate School of Biomedical Sciences student, now a Research Program Manager for the Hematological Malignancies Program and senior author Charles W.M. Roberts, MD, PhD, Executive Vice President and St. Jude Comprehensive Cancer Center director.

St. Jude Children’s Research Hospital scientists reversed an aggressive cancer, reverting malignant cells towards a more normal state. Rhabdoid tumors are an aggressive cancer which is missing a key tumor suppressor protein. Findings showed that with the missing tumor suppressor, deleting or degrading the quality control protein DCAF5 reversed the cancer cell state...

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Consistently Exercising 2–3 times a week over the Long Term linked to Lower Current Insomnia Risk

active vs lazy
Credit: Unsplash/CC0 Public Domain

Consistently exercising 2–3 times a week over the long term is linked to a lower current risk of insomnia as well as the ability to clock up the recommended 6–9 hours of shut-eye every night, suggests an international 10-year study published in the open access journal BMJ Open.

Regular exercise is associated with better overall health, and several studies have suggested that physical activity promotes better quality sleep and may improve symptoms of chronic insomnia, note the researchers.

But it’s not entirely clear how much gender, age, weight (BMI), overall fitness, general health, and exercise type contribute to this association, they add.

To explore this further, the researchers assessed the frequency, duration, and intensity of weekl...

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Scientists Identify a Key Driver of Myelin Repair

Scientists identify a key driver of myelin repair
Actin filaments (cyan) and an actin regulatory protein (magenta) in a differentiating oligodendrocyte. Credit: Brad Zuchero and Andrew Olson

New research from scientists at the Wu Tsai Neurosciences Institute at Stanford University has identified a key driver of myelination, the formation of protective fatty sheaths around nerve fibers.

Myelination is essential for the rapid transmission of electrical signals in the brain, facilitating everything from movement to thought. The breakdown or loss of this myelin sheath, as seen in conditions like multiple sclerosis and other neurodegenerative diseases, leads to significant cognitive and physical impairments.

The new findings have researchers excited about the potential for new avenues of treatment to regrow these insulating sheaths i...

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