Category Health/Medical

Diabetes drug cuts migraines in half by targeting brain pressure

A common diabetes drug may be the next big thing for migraine relief. In a clinical study, obese patients with chronic migraines who took liraglutide, a GLP-1 receptor agonist, experienced over 50% fewer headache days and significantly improved daily functioning without meaningful weight loss. Researchers believe the drugs ability to lower brain fluid pressure is the key, potentially opening a completely new way to treat migraines. The effects were fast, sustained, and came with only mild side effects.

A diabetes medication that lowers brain fluid pressure has cut monthly migraine days by more than half, according to a new study presented today at the European Academy of Neurology (EAN) Congress 2025.1

Researchers at the Headache Center of the University of Naples “Federico II” ...

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Scale of how chronic fatigue syndrome affects patients’ blood shown for first time

Scale of how myalgic encephalomyelitis/chronic fatigue syndrome affects patients' blood shown for first time
Study design and overview of results. Credit: EMBO Molecular Medicine (2025). DOI: 10.1038/s44321-025-00258-8

People with ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) have significant differences in their blood compared with healthy individuals, a new study reveals, suggesting a path toward more reliable diagnosis of the long-term debilitating illness. The paper is published in the journal EMBO Molecular Medicine.

The largest ever biological study of ME/CFS has identified consistent blood differences associated with chronic inflammation, insulin resistance, and liver disease.

Significantly, the results were mostly unaffected by patients’ activity levels, as low activity levels can sometimes hide the biological signs of illness, experts say.

The volume and cons...

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Simple insulin resistance test may also predict cognitive decline in Alzheimer’s patients

blood test
Credit: Artem Podrez from Pexels

Insulin resistance detected by routine triglyceride-glucose (TyG) index can flag people with early Alzheimer’s who are four times more likely to present rapid cognitive decline, according to new research presented at the European Academy of Neurology (EAN) Congress 2025.

Neurologists at the University of Brescia reviewed records of 315 non-diabetic patients with cognitive deficits, including 200 with biologically confirmed Alzheimer’s disease. All subjects underwent an assessment of insulin resistance using the TyG index and a clinical follow-up of three years.

The work is published in the journal Alzheimer’s & Dementia.

When patients were divided according to the TyG index, those in the highest third of the Mild Cognitive Impairment AD subgrou...

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Modified mRNA vaccine masquerades as a virus to trick the body into stronger immunity

Co-delivery of SpyC-mi3 and Pfs25-SpyT results in assembled particles displaying Pfs25 at high density. Credit: Nature Nanotechnology (2025). DOI: 10.1038/s41565-025-01889-1

A more effective vaccine technology may be on the horizon. In a new study in mice, researchers from the University of Copenhagen demonstrate that a simple addition to mRNA vaccines can significantly enhance their effectiveness. The innovation could become a powerful tool in the next pandemic. The next step is human trials.

During the COVID-19 pandemic, it wasn’t just face masks that became part of everyday conversation—so did a new vaccine technology: the mRNA vaccine.

As the first of its kind, the COVID-19 vaccine was developed using mRNA technology, which proved both highly effective against the virus a...

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