Category Health/Medical

Researchers Discover Key Metabolic Process Responsible for Rapid Immune Responses

T cell
Credit: Pixabay/CC0 Public Domain

Researchers from Children’s Hospital of Philadelphia (CHOP) identified a key metabolite in cells that helps direct immune responses and explains at a single cell level why immune cells that most efficiently recognize pathogens, vaccines, or diseased cells grow and divide faster than other cells.

The findings also indicate that a better understanding of this metabolite and its role in immune response could improve the design of immunotherapies and create longer-lived responses against different types of cancer as well as enhance vaccine strategies. The findings were published online by the journal Science Immunology in a paper titled “Single-cell NAD(H) levels predict clonal lymphocyte expansion dynamics.”

Antigens are foreign substances that our ...

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World’s first N-Channel Diamond Field-Effect Transistor for CMOS Integrated Circuits

World's first N-channel diamond field-effect transistor for CMOS integrated circuits

A National Institute for Materials Science (NIMS) research team has developed the world’s first n-channel diamond MOSFET (metal-oxide-semiconductor field-effect transistor). The developed n-channel diamond MOSFET provides a key step toward CMOS (complementary metal-oxide-semiconductor: one of the most popular technologies in the computer chip) integrated circuits for harsh environment applications, as well as the development of diamond power electronics. The research is published in Advanced Science.

Semiconductor diamond has outstanding physical properties such as ultra wide-bandgap energy of 5...

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Neurobiologists Uncover how Stress turns into Fear in the Brain in Conditions such as PTSD

Our nervous systems are naturally wired to sense fear. Whether prompted by the eerie noises we hear alone in the dark or the approaching growl of a threatening animal, our fear response is a survival mechanism that tells us to remain alert and avoid dangerous situations.Read More

Revealing a Hidden Threat: Researchers show Viral Infections pose Early Heart Risks

Revealing a hidden threat: Researchers show viral infections pose early heart risks
Graphical abstract. Credit: Circulation Research (2024). DOI: 10.1161/CIRCRESAHA.122.322437

In a potentially game-changing development, scientists with the Fralin Biomedical Research Institute at VTC have revealed a new understanding of sometimes fatal viral infections that affect the heart.

Traditionally, the focus has been on heart inflammation known as myocarditis, which is often triggered by the body’s immune response to a viral infection.

However, a new study led by James Smyth, associate professor at the Fralin Biomedical Research Institute, sheds new light on this notion, revealing that the virus itself creates potentially dangerous conditions in the heart before inflammation sets in.

The discovery, now online and set to appear in the March 29 issue of Circulation Res...

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