Category Technology/Electronics

A team of AI researchers at Universitat Politècnica de València, in Spain, has found that as popular LLMs (Large Language Models) grow larger and more sophisticated, they become less likely to admit to a user that they do not know an answer.

In their study published in the journal Nature, the group tested the latest version of three of the most popular AI chatbots regarding their responses, accuracy, and how good users are at spotting wrong answers.

As LLMs have become mainstream, users have become accustomed to using them for writing papers, poems or songs and solving math problems and other tasks, and the issue of accuracy has become a bigger...

The LLMs that have increasingly taken over the tech world are not “cheap” in many ways. The most prominent LLMs, such as GPT-4, took some $100 million to build in the form of legal costs of accessing training data, computational power costs for what could be billions or trillions of parameters, the energy and water needed to fuel computation, and the many coders developing the training algorithms that must run cycle after cycle so the machine will “learn.”

But, if a researcher needs to do a specializ...

CRISPR-Cas is used broadly in research and medicine to edit, insert, delete or regulate genes in organisms. TnpB is an ancestor of this well-known “gene scissors” but is much smaller and thus easier to transport into cells.

Using protein engineering and AI algorithms, University of Zurich researchers have now enhanced TnpB capabilities to make DNA editing more efficient and versatile, paving the way for treating a genetic defect for high cholesterol in the future. The work has been published in Nature Methods.

CRISPR-Cas systems, which consist of protein and RNA components, we...

The interlocking bricks, which can be repurposed many times over, can withstand similar pressures as their concrete counterparts. Engineers developed a new kind of reconfigurable masonry made from 3D-printed, recycled glass. The bricks could be reused many times over in building facades and internal walls.

What if construction materials could be put together and taken apart as easily as LEGO bricks? Such reconfigurable masonry would be disassembled at the end of a building’s lifetime and reassembled into a new structure, in a sustainable cycle that could supply generations of buildings using the same physical building blocks.

That’s the idea behind cir...