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Cleveland Clinic researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol.

The team, led by Stanley Hazen, M.D., Ph.D., discovered a link between 4PY, a breakdown product from excess niacin, and heart disease. Higher circulating levels of 4PY were strongly associated with development of heart attack, stroke and other adverse cardiac events in large-scale clinical studies. The researchers also showed in preclinical studies that 4PY directly triggers vascular inflammation which damages blood vessels and can lead to atherosclerosis over time.

The study, published in Nature Medicine, also details genetic links between 4PY and vascular inflammation...

Inspired by the color-changing ability of chameleons, researchers have developed a sustainable technique to 3D-print multiple, dynamic colors from a single ink.

“By designing new chemistries and printing processes, we can modulate structural color on the fly to produce color gradients not possible before,” said Ying Diao, an associate professor of chemistry and chemical and biomolecular engineering at the University of Illinois Urbana-Champaign and a researcher at the Beckman Institute for Advanced Science and Technology.

The study appears in the jour...

A study recently submitted to The Astronomical Journal continues to search for the elusive Planet Nine (also called Planet X), which is a hypothetical planet that potentially orbits in the outer reaches of the solar system and well beyond the orbit of the dwarf planet, Pluto.

The goal of this study, which is available on the pre-print server arXiv, was to narrow down the possible locations of Planet Nine and holds the potential to help researchers better understand the makeup of our solar system, along with its formation and evolutionary processes. So, what was the motivation behind this study regarding narrowing down the location of a potential Planet 9?

Proteins are nature’s polymers, governing biological processes at every level. A new study presents artificial proteins made using modern, precision polymers to intervene and alter natural processes towards a new way of developing therapeutics.

Researchers led by Northwestern University and the University of Wisconsin-Madison have introduced a pioneering approach aimed at combating neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease and Amyotrophic lateral scleros...