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Infections with cytomegalovirus (CMV) are extremely common and often pose no major threat to the vast majority of people. They can however be deadly for people whose immune system is weakened, e.g., after bone marrow transplantation. Current treatments against CMV infections are very limited and can have severe side effects. Researchers led by Prof...

Researchers have identified two ion channel switches that regulate the release of dopamine in the brain, a first step that might one day lead to therapeutics for a wide range of diseases and disorders that currently have few solutions.

The switches help regulate learning and motivational state in mice. Humans also have hundreds of these channels, which govern many chemical and hormonal processes that influence behavior and mood. The University of Washington School of Medicine research team hopes to identify drugs to target these channels. Those drug candidates could then be tested in clinical trials.

“The ability to precisely mani...

Partial recovery after ischemic stroke is possible, but the mechanisms involved in this process remain unclear...

Earth is rapidly warming and scientists are developing a variety of approaches to reduce the effects of climate change. István Szapudi, an astronomer at the University of Hawaiʻi Institute for Astronomy, has proposed a novel approach—a solar shield to reduce the amount of sunlight hitting Earth, combined with a tethered, captured asteroid as a counterweight. Engineering studies using this approach could start now to create a workable design that could mitigate climate change within decades.

The paper, “Solar radiation management with a tethered sun shield,” is published in Proceedings of the National Academy of Sciences.

One of the simplest approaches to reducing the global temperature is to shade the Earth from a fracti...