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Brain Cholesterol Regulates Alzheimer’s Plaques, study reveals

Brain cholesterol regulates Alzheimer's plaques, study reveals
Depletion of cholesterol in astrocytes (right) directly removes amyloid plaques and phosphorylated Tau (left, orange clusters) in an Alzheimer’s mouse model. Credit: Scott Hansen Lab, Scripps Research, Jupiter, Florida.

Advanced imaging technique shows how cholesterol regulates production of Alzheimer’s-associated amyloid beta protein in a type of brain cell.

A team co-led by scientists at Scripps Research has used advanced imaging methods to reveal how the production of the Alzheimer’s-associated protein amyloid beta (Aβ) in the brain is tightly regulated by cholesterol.

Appearing on line Thursday ahead of print in the Aug...

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Novel technique seamlessly converts Ammonia to ‘Green’ Hydrogen

A research team, led by Professor Guntae Kim in the School of Energy and Chemical Engineering at UNIST has announced a breakthrough in technology that efficiently converts liquid ammonia into hydrogen. Their findings have also attracted significant attention from academic research communities owing to its new analysis protocol, capable of finding optimal process environments.

In this study, the research team succeeded in producing green hydrogen (H2) in large quantities with a purity of nearly 100 percent by decomposing liquid ammonia (NH3) into electricity. Besides, according to the research team, such method consumed three times less power than hydrogen made using electrolysis of water.

Ammonia has emerged as an attractive potential hydrogen carrier due to its extremely high e...

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Black hole size revealed by its eating pattern

An artist’s impression of an accretion disk rotating around an unseen supermassive black hole. The accretion process produces random fluctuations in luminosity from the disk over time, a pattern found to be related to the mass of the black hole in a new study led by University of Illinois Urbana-Champaign researchers.
Graphic courtesy Mark A. Garlick/Simons Foundation

The feeding patterns of black holes offer insight into their size, researchers report. A new study revealed that the flickering in the brightness observed in actively feeding supermassive black holes is related to their mass.

Supermassive black holes are millions to billions of times more massive than the sun and usually reside at the center of massive galaxies...

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Meteorite Amino Acids derived from Substrates more widely available in the Early Solar System

Scientists have recreated the reaction by which carbon isotopes made their way into different organic compounds, challenging the notion that organic compounds, such as amino acids, were formed by isotopically enriched substrates. Their discovery suggests that the building blocks of life in meteorites were derived from widely available substrates in the early solar system.

Their findings were published online in Science Advances on April 28, 2021.

Carbonaceous meteorites contain the building blocks of life, including amino acids, sugars, and nucleobases. These meteorites are potential providers of these molecules to the prebiotic Earth.

The small organic molecules found in meteorites are generally enriched in a heavy carbon isotope (13C)...

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