
In the beginning, there were chemicals. Credit: Illustration by Max Englund
Life on Earth originated in an intimate partnership between the nucleic acids and peptides, according to two new papers from biochemists and biologists at the University of North Carolina at Chapel Hill and the University of Auckland. Their “peptide-RNA” hypothesis contradicts the widely-held “RNA-world” hypothesis, which states that life originated from nucleic acids and only later evolved to include proteins. The new papers show how recent experimental studies of two enzyme superfamilies surmount the tough theoretical questions about how complex life emerged on Earth more than 4 billion years ago.
“Until now, it has been thought to be impossible to conduct experiments to penetrate the origins of genetics,” said C...
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