Insulin resistance detected by routine triglyceride-glucose (TyG) index can flag people with early Alzheimer’s who are four times more likely to present rapid cognitive decline, according to new research presented at the European Academy of Neurology (EAN) Congress 2025.

Neurologists at the University of Brescia reviewed records of 315 non-diabetic patients with cognitive deficits, including 200 with biologically confirmed Alzheimer’s disease. All subjects underwent an assessment of insulin resistance using the TyG index and a clinical follow-up of three years.

The work is published in the journal Alzheimer’s & Dementia.

When patients were divided according to the TyG index, those in the highest third of the Mild Cognitive Impairment AD subgrou...

For decades, quantum computers that perform calculations millions of times faster than conventional computers have remained a tantalizing yet distant goal. However, a new breakthrough in quantum physics may have just sped up the timeline.

In an article titled “Efficient Magic State Distillation by Zero-Level Distillation” published in PRX Quantum, researchers from the Graduate School of Engineering Science and the Center for Quantum Information and Quantum Biology at the University of Osaka devised a method that can be used to prepare high-fidelity “magic states” for use in quantum computers with dramatically less overhead and unprecedented accuracy...

For years, astronomers have been searching for a mysterious ninth planet lurking in the dark outer reaches of our solar system. Now, a team of researchers have taken a completely different approach to this cosmic detective story—instead of looking for reflected sunlight, they’re hunting for the planet’s own heat signature.

The story begins with a puzzle in the outer solar system. Scientists noticed that small icy bodies called Kuiper Belt Objects, which orbit far beyond Neptune, seem to be clustered together in unusual ways...

A more effective vaccine technology may be on the horizon. In a new study in mice, researchers from the University of Copenhagen demonstrate that a simple addition to mRNA vaccines can significantly enhance their effectiveness. The innovation could become a powerful tool in the next pandemic. The next step is human trials.

During the COVID-19 pandemic, it wasn’t just face masks that became part of everyday conversation—so did a new vaccine technology: the mRNA vaccine.

As the first of its kind, the COVID-19 vaccine was developed using mRNA technology, which proved both highly effective against the virus a...