Long working hours may alter brain structure, preliminary findings suggest

Night shift
Credit: CC0 Public Domain

Long working hours may alter the structure of the brain, particularly the areas associated with emotional regulation and executive function, such as working memory and problem solving, suggest the findings of preliminary research, published online in Occupational & Environmental Medicine.

Ultimately, overwork may induce neuroadaptive changes that might affect cognitive and emotional health, say the researchers.

Long working hours have been linked to heightened risks of cardiovascular disease, metabolic disorders, and mental health issues. And the International Labor Organization (ILO) estimates that overwork kills more than 800,000 people every year, note the researchers.

While the behavioral and psychological consequences of overwork are reasonably w...

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Computer scientists discover new security vulnerability in Intel processors

Researchers discover new security vulnerability in Intel processors
To compute faster, a predictor in the computer processor anticipates certain calculation steps. Hackers can exploit these anticipations to bypass security barriers and access confidential information. In the illustration, a hacker manages to overcome the protective measures (privileges) at step 3. Credit: ETH Zurich / COMSEC, HK

Anyone who speculates on likely events ahead of time and prepares accordingly can react quicker to new developments. What practically every person does every day, consciously or unconsciously, is also used by modern computer processors to speed up the execution of programs. They have so-called speculative technologies which allow them to execute instructions on reserve that experience suggests are likely to come next...

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Astrophysicists explore our galaxy’s magnetic turbulence in unprecedented detail using a new computer model

A close up of colourful swirls and lines, a composite image of the Phantom Galaxy.
A composite image of the Phantom Galaxy and (inset) a high-resolution simulation of galactic turbulence with magnetic field lines in white. Photo: ESA/Webb, NASA & CSA, J. Lee and the PHANGS-JWST Team; Acknowledgement: J. Schmidt; Simulation: J. Beattie.

“Turbulence remains one of the greatest unsolved problems in classical mechanics,” says James Beattie, a postdoctoral researcher at the Canadian Institute for Theoretical Astrophysics (CITA) in the Faculty of Arts & Science at the University of Toronto, who also holds a joint appointment at Princeton University.

“This despite the fact that turbulence is ubiquitous: from swirling milk in our coffee to chaotic flows in the oceans, solar wind, interstellar medium, even the plasma between galaxies.

“The key distinction in astro...

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Forgotten cell clusters may hold key to diabetic neuropathy pain

Human dorsal root ganglia in a case of diabetic peripheral neuropathy show formation of Nageotte nodules (circled in pink), which appear to be a strong indicator of nerve cell death.

A phenomenon largely ignored since its discovery 100 years ago appears to be a crucial component of diabetic pain, according to new research from The University of Texas at Dallas’s Center for Advanced Pain Studies (CAPS).

Findings from a new study published in Nature Communications suggest that cell clusters called Nageotte nodules are a strong indicator of nerve cell death in human sensory ganglia. These could prove to be a target for drugs that would protect these nerves or help manage diabetic neuropathy.

“The key finding of our study is really a new view of diabetic neuropathic pain,” said Dr...

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