Fungal infections kill millions of people each year, and modern medicine is struggling to keep up. But researchers at McMaster University have identified a molecule that may help turn the tide—butyrolactolA, a chemical compound that targets a deadly, disease-causing fungi called Cryptococcus neoformans.

Infections caused by Cryptococcus are extremely dangerous. The pathogen, which can cause pneumonia-like symptoms, is notoriously drug-resistant, and it often preys on people with weakened immune systems, like cancer patients or those living with HIV. And the same can be said about other fungal pathogens, like Candida auris or Aspergillus fumigatus—both of which, like Cryptococcus, have been declared priority pathogens by the World Health Organization.

Despite the threat, thou...

AI might know where you’re going before you do. Researchers at Northeastern University used large language models, the kind of advanced artificial intelligence normally designed to process and generate language, to predict human movement.

How RHYTHM predicts human movement
RHYTHM, their innovative tool, “can revolutionize the forecasting of human movements,” forecasting “where you’re going to be in the next 30 minutes or the next 25 hours,” said Ryan Wang, an associate professor and vice chair of research in civil and environmental engineering at Northeastern.

The hope is that RHYTHM will improve domains like transportation and traffic planning to make our lives easier, but in extreme cases, RHYTHM could even be deployed to respond to natural dis...

Solar physicists say they have found a key source of intense gamma rays unleashed when Earth’s nearest star produces its most violent eruptions.

In findings published in Nature Astronomy, scientists at NJIT’s Center for Solar-Terrestrial Research (NJIT-CSTR) have pinpointed a previously unknown class of high-energy particles in the sun’s upper atmosphere responsible for generating the long-puzzling radiation signals observed during major solar flare events for decades.

The signals were traced back to a localized region in the solar corona during a powerful X8...

Depression, one of the most prevalent mental health disorders worldwide, is characterized by persistent feelings of sadness, impaired daily functioning and a loss of interest in daily activities, often along with altered sleeping and eating patterns. Past research findings suggest that stress can play a key role in the emergence of depressive symptoms, yet the biological processes via which it might increase the risk of depression remain poorly understood.

Researchers at Wenzhou Medical University, Capital Medical University and other institutes in China recently carried out a study investigating the biological processes that could ...