The LLMs that have increasingly taken over the tech world are not “cheap” in many ways. The most prominent LLMs, such as GPT-4, took some $100 million to build in the form of legal costs of accessing training data, computational power costs for what could be billions or trillions of parameters, the energy and water needed to fuel computation, and the many coders developing the training algorithms that must run cycle after cycle so the machine will “learn.”

But, if a researcher needs to do a specializ...

Noctilucent clouds were once thought to be a fairly modern phenomenon. A team of researchers recently calculated that Earth and the entire solar system may well have passed through two dense interstellar clouds, causing global noctilucent clouds that may have driven an ice age.

The event is thought to have happened 7 million years ago and would have compressed the heliosphere, exposing Earth to the interstellar medium.

Interstellar clouds are vast regions of gas and dust between the stars within galaxies. They are mostly made up of hydrogen along with a little helium and trace elements of heavier elements.

They are a key part of the life cycle of stars, providing the materials for new stars to be formed, and are seeded with elements after stars die...

CRISPR-Cas is used broadly in research and medicine to edit, insert, delete or regulate genes in organisms. TnpB is an ancestor of this well-known “gene scissors” but is much smaller and thus easier to transport into cells.

Using protein engineering and AI algorithms, University of Zurich researchers have now enhanced TnpB capabilities to make DNA editing more efficient and versatile, paving the way for treating a genetic defect for high cholesterol in the future. The work has been published in Nature Methods.

CRISPR-Cas systems, which consist of protein and RNA components, we...

Johns Hopkins Medicine scientists who arranged for 48 human bioengineered heart tissue samples to spend 30 days at the International Space Station report evidence that the low gravity conditions in space weakened the tissues and disrupted their normal rhythmic beats when compared to Earth-bound samples from the same source.

The scientists said the heart tissues “really don’t fare well in space,” and over time, the tissues aboard the space station beat about half as strongly as tissues from the same source kept on Earth.

The findings, they say, expand scientists’ knowledge of low gravity’s potential effects on astronauts’ survival and health during long space missions, and they may serve as models for study...