‘Gene Misbehavior’ Widespread in Healthy People

'Gene misbehavior' widespread in healthy people
Identification of misexpression events and characterization of misexpressed genes. Credit: The American Journal of Human Genetics (2024). DOI: 10.1016/j.ajhg.2024.06.017

New insights into the prevalence and mechanisms of gene misexpression in a healthy population could help in diagnosing and developing treatments for complex diseases.

Scientists have uncovered that ‘gene misbehaviour’ – where genes are active when they were expected to be switched off – is a surprisingly common phenomenon in the healthy human population.

The team also identify several mechanisms behind these gene activity errors. This may help inform precision medicine approaches and enable the development of targeted therapies to correct expression.

Researchers from the Wellcome Sanger Institute, the Univer...

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Researchers Develop Innovative Battery Recycling Method

Illustration of lithium ion batteries
3D rendering of lithium ion batteries

A research team at Rice University led by James Tour, the T.T. and W.F. Chao Professor of Chemistry and professor of materials science and nanoengineering, is tackling the environmental issue of efficiently recycling lithium ion batteries amid their increasing use.

The team has pioneered a new method to extract purified active materials from battery waste as detailed in the journal Nature Communications on July 24. Their findings have the potential to facilitate the effective separation and recycling of valuable battery materials at a minimal fee, contributing to a greener production of electric vehicles (EVs).

“With the surge in battery use, particularly in EVs, the need for developing sustainable recycling methods is pressing,” Tour said.

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Dark Matter Flies Ahead of Normal Matter in Mega Galaxy Cluster Collision

This artist's concept depicts a collision between two massive clusters of galaxies.
This artist’s concept shows what happened when two massive clusters of galaxies, collectively known as MACS J0018.5, collided: The dark matter in the galaxy clusters (blue) sailed ahead of the associated clouds of hot gas, or normal matter (orange). Both dark matter and normal matter feel the pull of gravity, but only the normal matter experiences additional effects like shocks and turbulence that slow it down during collisions.Credit: W.M. Keck Observatory/Adam Makarenko

The research provides a unique look at how this matter decoupling proceeds. Astronomers have untangled a messy collision between two massive clusters of galaxies in which the clusters’ vast clouds of dark matter have decoupled from the so-called normal matter...

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Handheld Device Offers Lab-Quality Diagnostic Testing

Handheld device offers lab-quality diagnostic testing

The LIAMT handheld processor features a window which the user can look through to view fluorescent virus detection signals. Credit: Advanced Science (2024). DOI: 10.1002/advs.202310066

Because of its high accuracy, laboratory-based polymerase chain reaction (PCR) testing is the gold standard for infectious disease diagnostics. However, PCR technology requires highly trained staff and costly equipment, hindering its availability, especially in low-resource settings. New research suggests a different kind of test could be more streamlined without sacrificing performance.

A platform technology developed by researchers at the University of Connecticut uses similar techniques as PCR testing, but within a handheld device rather than several benchtop machines.

In a study publish...

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