Acetylcholine receptors, also known as nicotinic receptors
Several scientific studies have indicated that nicotine may be beneficial for memory function. Scientists set out to shed further light on the properties attributed to nicotine – which is known to have an adverse effect on health – by determining the precise structure of the nicotinic receptors in the hippocampus region of the brain. Using mouse models for Alzheimer’s disease, they identified the β2 subunit of the nicotinic receptor as a target that, if blocked, prevents the memory loss associated with Alzheimer’s.
Alzheimer’s disease is characterized by two types of lesion: amyloid plaques and neurofibrillary degeneration...
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