3-step pretargeted radioimmunotherapy tagged posts

Curative Multicycle Radioimmunotherapy Monitored by Quantitative SPECT/CT-Based Theranostics, Using Bispecific Antibody Pretargeting Strategy in Colorectal Cancer. Journal of Nuclear Medicine, 2017; 58 (11): 1735 DOI: 10.2967/jnumed.117.193250

Novel 3-step pretargeted radioimmunotherapy offers safe, effective treatment. In this study with a mouse model, researchers achieved a 100% cure rate -without any treatment-related toxic effects. Until now, radioimmunotherapy (targeted therapy) of solid tumors using antibody-targeted radionuclides has had limited therapeutic success. “This research is novel because of the benchmarks reached by the treatment regimen, in terms of curative tumor doses, with non-toxic secondary radiation to the body’s normal tissues,” explains Steven M...