Schematic representation of this research.
These cells – capable of generating all cell types in the body – could be used as the ‘Lego bricks’ to build tissue constructs, larger structures of tissues, and potentially even micro-organs. “It was really exciting to see that we could grow embryoid body in such a controlled manner,” explains Wei Sun. “The grown embryoid body is uniform and homogenous, and serves as a much better starting point for further tissue growth.”
The researchers, based at Tsinghua University, Beijing, China, and Drexel University, Philadelphia, USA, used extrusion-based 3D printing to produce a grid-like 3D structure to grow embryoid body with cell viability and rapid self-renewal for 7 days while maintaining high pluripotentcy.
Images of the printed cellular model with...
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