Researchers at Duke University and North Carolina State University have discovered a handful of new CRISPR-Cas systems that could add to the capabilities of the already transformational gene editing and DNA manipulation toolbox.
Of the new recruits, one system from bacteria commonly found in dairy cows shows particular promise for human health. Its efficiency is on par with the original and most widely used CRISPR-Cas system, but its small size allows it to be more easily packaged for delivery to human cells. It also can target specific gene sequences that other systems cannot, and human immune systems are unlikely to have been exposed to it.
The results appear online March 14 in the Proceedings of the National Academy of Sciences (PNAS).
CRISPR-Cas9 burst onto the broader sc...
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