AbD09097 tagged posts

Osteoporosis: Antibody Crystallized

Model of a Sclerostin-fragment (green) bound to the antibody AbD09097 (heavy and light chain in cyan and red, respectively; surface representation in grey). Credit: Thomas Mueller

Model of a Sclerostin-fragment (green) bound to the antibody AbD09097 (heavy and light chain in cyan and red, respectively; surface representation in grey). Credit: Thomas Mueller

Osteoporosis particularly affects elderly women and the risk of suffering fractures rises. As prophylaxis patients are advised to have a healthy diet and perform physical exercises; when the risk of bone fractures is high, medicine preventing further bone loss is prescribed in addition. Inhibiting protein sclerostin could probably help treating the bone-loss disease osteoporosis. Bone resorption diminishes and bone re-growth is stimulated...

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