acetate-using-ACSS2 in effector T cells tagged posts

Your Immune Cells are what they Eat

Two T cells whose nutritional choices have changed their identity. On the left, a blue T cell prefers acetate and is active, able to continue fighting. On the right, a red T cell prefers citrate and is exhausted, no longer able to fight effectively.
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Credit: Salk Institute

Salk scientists establish novel Link between cell nutrition and identity, say targeting nutrient-dependent activity could improve immunotherapies.

The decision between scrambled eggs or an apple for breakfast probably won’t make or break your day. However, for your cells, a decision between similar microscopic nutrients could determine their entire identity...

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