activating optogluram tagged posts

Optical control of a Neuroreceptor Alleviates Chronic Pain

View of synapses in the amygdala of a mouse, obtained using a confocal microscope. mGlu4 receptors in red, and mGlu1a receptors in green. The white bar bottom right corresponds to 5 ?m. Credit: Zussy et al., 2016

View of synapses in the amygdala of a mouse, obtained using a confocal microscope. mGlu4 receptors in red, and mGlu1a receptors in green. The white bar bottom right corresponds to 5 ?m. Credit: Zussy et al., 2016

Pain serves as a valuable warning signal, but when it becomes chronic, pain should be considered as a real disease. An international team including research scientists from the CNRS and INSERM has identified and controlled one of the centers associated with chronic pain. This work, published on 20 December 2016 in Molecular Psychiatry, made it possible to relieve the symptoms in mice and demonstrated the ability of the brain to remedy this problem.

While around 20% of the European population has experienced episodes of chronic pain, treatments are only effective in fewer than half...

Read More