activity-regulated cytoskeleton-associated protein (Arc) tagged posts

Overweight adults spend more of their sleep in REM stage than healthy weight adults do. An individual’s body composition and caloric intake can influence time spent in specific sleep stages, according to results of a new study from Perelman School of Med at PennU that will be presented at SLEEP 2016, 30th annual meeting of the Associated Professional Sleep Societies LLC.

In the study, 36 healthy adults experienced 2 consecutive nights of 10 hrs in bed per night at the Hospital of the University of Pennsylvania.Polysomnography was recorded on the second night. Body composition and resting energy expenditure were assessed on the morning following the first night of sleep. Food/drink intake was measured each day.

The Penn team found that BMI, body fat percentage and resting energy expenditur...

Orosensory stimulation produced by consuming a sweetened solution and possibly the hedonic value of that sweet stimulation induces synaptic plasticity in dHC CA1 neurons in an experience-dependent manner. Collectively, these findings are consistent with our hypothesis that dHC neurons form a memory of a meal.

Neurons in the dorsal hippocampus, the part of the brain that is critical for episodic memory, are activated by consuming sweets. Episodic memory is the memory of autobiographical events experienced at a particular time and place.

In the study, a meal consisting of a sweetened solution, either sucrose or saccharin, significantly increased the expression of the synaptic plasticity marker called activity-regulated cytoskeleton-associated protein (Arc) in dorsal hippocampal neurons in ra...