adalimumab (Humira) tagged posts

The New Pill can Inject Large Quantities of Monoclonal Antibodies and other drugs into the Lining of the Stomach after being Swallowed.

diagram of antibodies entering stomach
Caption:The new pill can inject large quantities of monoclonal antibodies and other drugs into the lining of the stomach after being swallowed.
Credits:Image: courtesy of the researchers

In recent years, scientists have developed monoclonal antibodies — proteins that mimic the body’s own immune defenses — that can combat a variety of diseases, including some cancers and autoimmune disorders such as Crohn’s disease. While these drugs work well, one drawback to them is that they have to be injected.

A team of MIT engineers, in collaboration with scientists from Brigham and Women’s Hospital and Novo Nordisk, is working on an alternative delivery strategy that could make it much easier for patients to benefit from monoclonal antibodies and other drugs that usually have to be injected...

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