A mouse’s fat cells (red) are shown surrounded by a network of blood vessels (green). Source: Daniela Malide, National Heart, Lung, and Blood Institute, National Institutes of Health
UC SF scientists have found a surprising new avenue for potential therapies to reduce risk of type 2 diabetes and other metabolic disorders associated with chronic tissue inflammation in obesity. Inflammation in obesity may be caused, at least in part, by a completely different mechanism from the one that controls normal immune responses. The research shows saturated fats “short-circuit” both mouse and human immune cells, producing an inappropriate inflammatory response as a consequence...
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