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    Age-Related Disease tagged posts

    Uncovering a ‘Smoking Gun’ in Age-Related Disease

    December 5, 2016, Categories  Biology/Biotechnology, Health/Medical

    Image: Old C. elegans expressing a specific alternative splicing event tagged by either green or red fluorescent protein, well-fed (left) or on dietary restriction (right). Worms on dietary restriction maintain a youthful splicing pattern (as seen in young worms) compared to the well-fed worm population at the same age. Credit: Image courtesy of Harvard T.H. Chan School of Public Health

    Image: Old C. elegans expressing a specific alternative splicing event tagged by either green or red fluorescent protein, well-fed (left) or on dietary restriction (right). Worms on dietary restriction maintain a youthful splicing pattern (as seen in young worms) compared to the well-fed worm population at the same age. Credit: Image courtesy of Harvard T.H. Chan School of Public Health

    For the 1st time, a causal link between RNA splicing and aging has been revealed. The finding sheds light on the biological role of splicing in lifespan and suggests that manipulating specific splicing factors in humans might help promote healthy aging...

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