Mice that mimic Alagille syndrome are born without the branches of the biliary tree (A), but show a near-normal appearing biliary system at adult age (B). To build the missing branches, liver cells switch identity and form tubes, shown in green, that connect to the trunk of the biliary tree, shown in blue (C). The images are part of a study about liver regeneration published in Nature by scientists at Cincinnati Children’s and the University of California San Francisco. Credit: Cincinnati Children’s
By studying a rare liver disease called Alagille syndrome, scientists from Cincinnati Children’s and the University of California San Francisco (UCSF) have discovered the mechanism behind an unusual form of tissue regeneration that may someday reduce the need for expensive and difficult-to-obta...
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