alternative to liver transplantation tagged posts

Injectable ‘satellite livers’ could offer an alternative to liver transplantation

Researchers used a microfluidic device to generate hydrogel microspheres of uniform shape and size. These spheres are then mixed with hepatocytes and injected into the body, where they form stable mini livers.
Credits:Credit: Courtesy of the Bhatia Lab

More than 10,000 Americans who suffer from chronic liverdisease are on a waitlist for a liver transplant, but there are not enough donated organs for all of those patients. Additionally, many people with liver failure aren’t eligible for a transplant if they are not healthy enough to tolerate the surgery.

To help those patients, MIT engineers have developed “mini livers” that could be injected into the body and take over the functions of the failing liver.

In a new study in mice, the researchers showed that these injected liver cell...

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