The largest nationwide clinical trial to study high-dose resveratrol long-term in people with mild to moderate Alzheimer’s disease found that a biomarker that declines when the disease progresses was stabilized in people who took the purified form of resveratrol. Resveratrol is a naturally occurring compound found in foods such as red grapes, raspberries, dark chocolate and some red wines.
The resveratrol clinical trial was a randomized, phase II, placebo-controlled, double blind study in 119 patients with mild to moderate dementia due to Alzheimer’s disease. An “investigational new drug” application was required by FDA to test the pure synthetic (pharmaceutical-grade) resveratrol in the study. It is not available commercially in this form...
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