AMPA receptors tagged posts

Protein synthesis regulatory factor RNG105/caprin1 is essential for long-term memory formation.

The research group of Associate Professor Nobuyuki Shiina of the National Institute for Basic Biology have revealed that the function of RNG105 (aka Caprin1) is essential for the formation of long-term memory. RNG105 is a factor involved in protein synthesis in the vicinity of synapses, which transmit information between neurons. Mice who have lost RNG105 in the cerebrum and hippocampus can form short-term memories of several minutes, but the research group has shown that long-term memory, developed over several days to one week, does not form in these mice...