anterior cingulate cortex (ACC) tagged posts

Neuroscientists identify a brain circuit that helps break decisions down into smaller pieces. The study sheds light on how the brain reasons about probable causes of failure after a hierarchy of decisions. When making a complex decision, we often break the problem down into a series of smaller decisions. For example, when deciding how to treat a patient, a doctor may go through a hierarchy of steps – choosing a diagnostic test, interpreting the results, and then prescribing a medication.

Making hierarchical decisions is straightforward when the sequence of cho...

Unusually weak neural responses (yellow spot) in the anterior cingulate cortex: autistic people find it hard to imagine themselves in somebody else’s position. Credit: Joshua Balsters / ETH Zurich

Brain researchers at ETH Zurich and other universities have shown for the first time that a region of the brain associated with empathy only activates very weakly in autistic people. This knowledge could help to develop new therapies for those affected by autism. Professor Nicole Wenderoth and her senior scientist Joshua Balsters have used fMRI from autistic adolescents to discover unusual activity in a particular region of the brain, the anterior cingulate cortex (ACC).

The researchers were aware that activity in this part of the brain is coupled with the “theory of mind”, which makes it possi...

To understand human behaviors, it is crucial to understand the motives behind them. So far, there was no direct way to identify motives. Psychologist and neuroscientist Grit Hein, Ernst Fehr et al found that the way relevant brain regions communicate with each other is altered depending on the motives driving a specific behavioral choice. This interplay between brain regions allowed them to identify the underlying motives. These motives could not be uncovered by observing the person’s choices, or based on the brain regions that are activated during the decision-making.

Empathy-based altruism is primarily characterized by a positive connectivity from the anterior cingulate cortex (ACC) to the anterior insula (AI), whereas reciprocity-based altruism additionally invokes strong positive conn...