anti-B7-H3 antibody therapy tagged posts

Novel Immunotherapy Agent Safe, shows promise against High-risk Prostate Cancers

Shenderov
Prostate cancer nodule with dramatized anti-B7-H3 antibody therapy Credit: Adobe stock per investigator

A new drug, a monoclonal antibody known as enoblituzumab, is safe in men with aggressive prostate cancer and may induce clinical activity against cancer throughout the body, according to a phase 2 study led by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy. If confirmed in additional studies, enoblituzumab could become the first promising antibody-based immunotherapy agent against prostate cancer.

In a clinical trial, 32 men with high-risk or very high-risk prostate cancers who were scheduled for prostate cancer surgery were treated with six weekly infusions of enoblituzumab prior to surgery, and were followed fo...

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