Antibody Binding tagged posts

As COVID Cases Rise again, what do I need to know about the New FLiRT Variants?

As COVID cases rise again, what do I need to know about the new FLiRT variants?
The proportion of COVID cases caused by FLiRT subvariants is rising in NSW. Credit: NSW Health

We’ve now been living with COVID for well over four years. Although there’s still much to learn about SARS-CoV-2 (the virus that causes COVID) at least one thing seems clear: it’s here to stay.

From the original Wuhan variant, to delta, to omicron, and several others in between, the virus has continued to evolve.

New variants have driven repeated waves of infection and challenged doctors and scientists seeking to understand this changing virus’ behavior.

Now, we are faced with a new group of variants, the so-called “FLiRT” variants, which appear to be contributing to a rising wave of COVID infections around Australia and elsewhere...

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Never-before-seen Antibody Binding, informing Liver Cancer, antibody design

A structural snapshot of a phosphohistidine analogue (ball and stick model) nestled at the interface between different areas (green, brown) of a phosphohistidine antibody. Such structures provide insights into the molecular properties of the antibodies, which makes them useful for revealing elusive phosphohistidine-containing proteins in cells.
Credit: Salk Institute

Xray crystallography and recombinant antibodies uncover workings of an elusive molecule central to human health. In structural biology, some molecules are so unusual they can only be captured with a unique set of tools...

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