Select Antieleptic drugs target mechanisms of epileptogenesis involving amyloid β and tau. Subclinical epileptiform activity in patients with Alzheimer’s disease can lead to accelerated cognitive decline and may be treated with AEDs like Levetiracetam.
Feasibility study suggests suppressing seizure-like activity may help patients. In the last decade, mounting evidence has linked seizure-like activity in the brain to some of the cognitive decline seen in patients with Alzheimer’s disease. Patients with Alzheimer’s disease have an increased risk of epilepsy and nearly half may experience subclinical epileptic activity – disrupted electrical activity in the brain that doesn’t result in a seizure but which can be measured by electroencephalogram (EEG) or other brain scan technology.
In a rece...
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