anxiety and depression tagged posts

New Light on Link between Gut Bacteria and Anxiety

GF male mice display dysregulated network of miRNA expression in the amygdala and PFC. a Schematic representation of experimental design. b Donut plot representing the number of increased and decreased miRNA in the amygdala (outer plot) and PFC (inner plot) when comparing CON vs GF mice. c Volcano plot representing fold change against significance (P < 0.05) between CON and GF mice in the amygdala and PFC. d Venn diagram reporting overlapping differentially regulated miRNA between all three experimental groups in the amygdala representing the effect of colonization of GF mice on miRNAs. e Represents the impact of colonization of GF mice in the PFC. f Number of miRNAs by name that are normalized by colonization and common in both brain regions. g Number of microRNAs that are commonly dysregulated in both brain regions. Highlighted in red are those that are oppositely regulated in both brain regions

GF male mice display dysregulated network of miRNA expression in the amygdala and PFC. a Schematic representation of experimental design. b Donut plot representing the number of increased and decreased miRNA in the amygdala (outer plot) and PFC (inner plot) when comparing CON vs GF mice. c Volcano plot representing fold change against significance (P < 0.05) between CON and GF mice in the amygdala and PFC. d Venn diagram reporting overlapping differentially regulated miRNA between all three experimental groups in the amygdala representing the effect of colonization of GF mice on miRNAs. e Represents the impact of colonization of GF mice in the PFC. f Number of miRNAs by name that are normalized by colonization and common in both brain regions...

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Comparing your Index and Ring Fingers shows if you are likely to be Anxious or Good Athlete

Researchers used a common photocopy machine to measure the lengths of the index and ring fingers of 42 women. Half of these women were asked to solve different mental tasks after they had been given a drop of testosterone on their tongue. The goal was to determine the differences in how men's and women's brains work, and the significance of finger length and testosterone levels. Credit: Carl Pintzka / Kolbjørn Skarpnes, NTNU.

Researchers used a common photocopy machine to measure the lengths of the index and ring fingers of 42 women. Half of these women were asked to solve different mental tasks after they had been given a drop of testosterone on their tongue. The goal was to determine the differences in how men’s and women’s brains work, and the significance of finger length and testosterone levels. Credit: Carl Pintzka / Kolbjørn Skarpnes, NTNU.

It is well-known that adults whose index finger is shorter than their ring finger were exposed to greater amounts of testosterone when they were in the womb. Both women and men with this characteristic are – on average – better equipped to solve mentally demanding 3D rotation tasks as adults...

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Gastrointestinal Disorders involve both Brain-to-Gut and Gut-to-Brain Pathways

The biopsychosocial model of Irritable Bowel Syndrome.

The biopsychosocial model of Irritable Bowel Syndrome.

New research indicates that in patients with irritable bowel syndrome (IBS) or indigestion, there is a distinct brain-to-gut pathway, where psychological symptoms begin first, and separately a distinct gut-to-brain pathway, where gut symptoms start first. In the study, higher levels of anxiety and depression were significant predictors of developing IBS or indigestion within 1 year. People who did not have elevated levels of anxiety and depression at the start of the study but had documented IBS or indigestion reported significantly higher levels of anxiety and depression after 1 year.

The researchers calculated that in one-third of individuals, a mood disorder precedes gastrointestinal disorder, but in two-thirds a gastrointestinal di...

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