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    APT1 tagged posts

    Study reveals Obesity-related Trigger that can lead to Diabetes

    January 12, 2023, Categories  Biology/Biotechnology, Health/Medical

    Researchers at Washington University School of Medicine in St. Louis have found that a defect in an enzyme called APT1 interferes with the ability to secrete insulin, contributing to the development of Type 2 diabetes in people who are overweight or obese. In this microscopic image of the surface of an insulin-secreting beta cell from a mouse with diabetes, granules containing insulin are green; granules containing a protein affected by APT1 are red; and the yellow granules are those that release excess insulin due to a defect in APT1.

    Many with elevated insulin levels also have defects in an enzyme key to fatty acid processing...

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