astrocyte-produced cholesterol tagged posts

Brain Cholesterol Regulates Alzheimer’s Plaques, study reveals

Brain cholesterol regulates Alzheimer's plaques, study reveals
Depletion of cholesterol in astrocytes (right) directly removes amyloid plaques and phosphorylated Tau (left, orange clusters) in an Alzheimer’s mouse model. Credit: Scott Hansen Lab, Scripps Research, Jupiter, Florida.

Advanced imaging technique shows how cholesterol regulates production of Alzheimer’s-associated amyloid beta protein in a type of brain cell.

A team co-led by scientists at Scripps Research has used advanced imaging methods to reveal how the production of the Alzheimer’s-associated protein amyloid beta (Aβ) in the brain is tightly regulated by cholesterol.

Appearing on line Thursday ahead of print in the Aug...

Read More