atherosclerotic cardiovascular disease (ASCVD) tagged posts

Cholesterol may Not be the Only Lipid involved in Trans Fat-driven Cardiovascular Disease

Cholesterol is not the only lipid involved in trans fat-driven cardiovascular disease
Graphical abstract. Credit: Cell Metabolism (2024). DOI: 10.1016/j.cmet.2024.10.016

Excess cholesterol is known to form artery-clogging plaques that can lead to stroke, arterial disease, heart attack, and more, making it the focus of many heart health campaigns. Fortunately, this attention to cholesterol has prompted the development of cholesterol-lowering drugs called statins and lifestyle interventions like dietary and exercise regimens. But what if there’s more to the picture than just cholesterol?

New research from Salk Institute scientists describes how another class of lipids, called sphingolipids, contributes to arterial plaques and atherosclerotic cardiovascular disease (ASCVD)...

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