bacteriophage tagged posts

Proofreading the book of life: Gene Editing made Safer

The graphic illustrates the technique described in the new study. A version of the Cas9 protein used in CRISPR gene editing has been mutated. While this protein, seen in blue, retains its proper functioning, it remains “immunosilent”–hidden from predation as a foreign entity by the immune system’s T cells (seen in brown).
Credit: Graphic by Jason Drees

Scientists describe a method of rendering the gene editing tool CRISPR-Cas9 ‘immunosilent,’ potentially allowing the editing and repair of genes to be accomplished reliably and stealthily...

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