BAM15 tagged posts

Drug researcher develops ‘Fat Burning’ Molecule

Schematic showing key energy production pathways. Metabolites colour-coded by fold change of WD + BAM15 compared with WD, scale of twofold positive (red) to twofold negative (blue).

Scientists have recently identified a small mitochondrial uncoupler, named BAM15, that decreases the body fat mass of mice without affecting food intake and muscle mass or increasing body temperature.

Obesity affects more than 40 percent of adults in the United States and 13 percent of the global population. With obesity comes a variety of other interconnected diseases including cardiovascular disease, diabetes, and fatty liver disease, which makes the disease one of the most difficult — and most crucial — to treat.

“Obesity is the biggest health problem in the United States...

Read More