This visual abstract depicts how drugging the gut microbiota with a nonlethal inhibitor that blocks production of the metabolite trimethylamine reduces the formation of atherosclerotic lesions and represents the first step toward treatment of cardiometabolic diseases by targeting the microbiome. Credit: Wang et al./Cell 2015
Dietary supplementation with a compound that is naturally abundant in red wine and olive oil prevented gut microbes from turning unhealthy foods into metabolic byproducts that clog arteries. The findings suggest that a Mediterranean diet exerts its beneficial health effects by altering the activity of gut microbes...
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