Transcriptional control of bcat-1-mediated regulation of lifespan.
Out of a ‘haystack’ of 40,000 genes from 3 different organisms, scientists have found genes involved in physical aging. If you influence only 1 of these genes, the healthy lifespan of lab animals is extended – and possibly that of humans, too.
Until now, this was mostly limited to genes of individual model organisms such as the C. elegans nematode, which revealed that ~1% of its genes could influence life expectancy. However, researchers have long assumed that such genes arose in the course of evolution and in all living beings whose cells have a preserved a nucleus – from yeast to humans.
Researchers at ETH Zurich and JenAge consortium from Jena have now systematically gone through genomes of 3 different organisms in searc...
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