bile acid-methylcysteamine (BA–MCY) tagged posts

Diet, Microbes and Fat: A new pathway controlling levels of body fat and cholesterol

Diet, microbes and fat: A new pathway controlling levels of body fat and cholesterol
Lipid accumulation in a murine model of fatty liver disease, visualized by color-enhanced lipid droplets (pink) in liver tissue (green). Superimposed chemical structure of a newly discovered bile acid conjugate. Credit: Dr. Mohammad Arifuzzaman, Dr. Christopher Parkhurst, Dr. Frank Schroeder, and Dr. David Artis.

Beneficial gut microbes and the body work together to fine-tune fat metabolism and cholesterol levels, according to a new preclinical study by investigators from Weill Cornell Medicine and the Boyce Thompson Institute at Cornell University’s Ithaca campus.

The research is published in the journal Nature.

The human body has co-evolved with the beneficial microbes that live in the gut (termed the microbiota), resulting in mutually favorable relationships that aid in the d...

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